Sinegin 3 - Names and Identifiers
Sinegin 3 - Physico-chemical Properties
Molecular Formula | C75H112O35
|
Molar Mass | 1573.67 |
Density | 1.54±0.1 g/cm3 (20 ºC 760 Torr) |
Melting Point | 254-256°C |
Specific Rotation(α) | -10.2 (c, 1.08 in MeOH) |
Solubility | Soluble in water, ethanol, methanol and other solvents, insoluble in petroleum ether, chloroform, ethyl acetate. |
Appearance | White needle crystal |
pKa | 4.14±0.70(Predicted) |
Storage Condition | 2-8℃ |
Sensitive | Easily absorbing moisture |
MDL | MFCD28124358 |
Physical and Chemical Properties | White crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, from Willd, Polygala tenuifolia of Polygala tenuifolia.. |
Sinegin 3 - Reference
Reference Show more | 1. [IF=3.935] Ruimei Lin et al."Global identification and determination of the major constituents in Kai-Xin-San by ultra-performance liquid chromatography-quadrupole-Orbitrap mass spectrometry and gas chromatography-mass spectrometry."J Pharmaceut Biomed. 2021 Nov;206 |
Sinegin 3 - Introduction
Onjisaponin B is an active ingredient extracted from the traditional Chinese medicine Polygala. Its chemical structure is protocatechol structure with multiple biological activities. The common properties of Onjisaponin B are as follows:
1. Water solubility: Onjisaponin B is easily soluble in water and can be dissolved under appropriate conditions.
2. Biological activity: Onjisaponin B has antioxidant, anti-inflammatory, antibacterial, anti-tumor and other biological activities, has a certain health and medicinal value.
The use of Onjisaponin B mainly includes the following aspects:
1. Medicinal: Onjisaponin B can be used as the main active ingredient of Chinese medicine Polygala, used to treat digestive system diseases, nervous system diseases, cardiovascular diseases, etc.
2. Health care products: Onjisaponin B is often used to make health care products, with anti-aging, improve immunity, antioxidant and other effects.
The preparation method of Onjisaponin B generally adopts the method of separation and extraction. First, Polygala is ground into powder, and then its active ingredients are separated from other impurities by solvent extraction. In a specific operation, extraction can be performed using a solvent such as alcohols and ethers.
Regarding the safety information of Onjisaponin B, there is no clear report showing that it has significant toxic and side effects. But still need to pay attention to the following points when using:
1. Avoid excessive use: as far as possible in accordance with the doctor or health care products manufacturers recommended use, avoid more than the recommend dose.
2. Use with caution for those who are allergic: Some people may be allergic to Onjisaponin B, and pay attention to individual allergic reactions when using it.
Last Update:2024-04-10 22:40:09